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Article

ABCG2, SCN1A and CYP3A5 genes polymorphism and drug-resistant epilepsy in children: A case-control study.

Seizure - 1 Apr 2022

Mousavi Seyedeh Farnaz, Hasanpour Kazem, Nazarzadeh Milad, Adli Abolfazl, Bazghandi Malihe Sadat, Asadi Alireza, Rad Abolfazl, Gholami Omid

Abstract excerpt

PURPOSE: Drug Resistant -Epilepsy is still a major challenge in pharmacotherapy of epilepsy. Pharmacogenetic pathways are one of the most important elements that can help clinicians determine medication response and provide more efficient drug therapy, especially in cases of drug resistance. Genetic alterations in drug target and transporter proteins, in part, could explain the development of drug-resistant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35338956
DOI: 10.1016/j.seizure.2022.03.009

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