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Article

Insights into the role of Bcl6 in follicular Th cells using a new conditional mutant mouse model.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2013

Hollister Kristin, Kusam Saritha, Wu Hao, Clegg Ninah, Mondal Arpita, Sawant Deepali V, Dent Alexander L

Abstract excerpt

The transcriptional repressor Bcl6 controls development of the follicular Th cell (T(FH)) lineage, but the precise mechanisms by which Bcl6 regulates this process are unclear. A model has been proposed whereby Bcl6 represses the differentiation of T cells into alternative effector lineages, thus favoring T(FH) cell differentiation. Analysis of T cell differentiation using Bcl6-deficient mice has been complicated...

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Identifiers

PMID: 23980208
DOI: 10.4049/jimmunol.1300378
PMCID: PMC3783642

Genes

CXCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Insights into the role of Bcl6 in follicular Th cells using a new conditional mutant mouse model.PMID 23980208Read ↗

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