Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequency and clinical impact of WT1 mutations in the context of CEBPA-mutated acute myeloid leukemia.

Hematology (Amsterdam, Netherlands) - 1 Dec 2022

Wang Ting, Hua Haiying, Wang Zheng, Wang Biao, Cao Liujun, Qin Wei, Wu Pin, Cai Xiaohui, Chao Hongying, Lu XuZhang

Abstract excerpt

INTRODUCTION: Several studies have confirmed that mutations in the Wilms tumor 1 (WT1) gene occur in adult acute myeloid leukemia (AML). However, few data are available regarding the incidence of WT1 mutations in CEBPAmut AML and their impact. METHODS: We retrospectively analyzed the frequency and clinical impact of WT1 mutations in 220 newly diagnosed AML patients with CEBPA mutations(CEBPAmut). Chromosome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCAAT-Enhancer-Binding Proteins
Share to In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Prognosis

Share to WT1 Proteins

Source

Identifiers

PMID: 36066283
DOI: 10.1080/16078454.2022.2103964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequency and clinical impact of WT1 mutations in the context of CEBPA-mutated acute myeloid leukemia.PMID 36066283Read ↗

Frequency and Clinical Impact of WT1 Mutations in the Context of CEBPA-Mutated Acute Myeloid LeukemiaSemantic proximity Read ↗

WT1 mutations are secondary events in AML, show varying frequencies and impact on prognosis between genetic subgroups.Semantic proximity Read ↗

Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia.Semantic proximity Read ↗

Prognostic impact of Wilms tumor gene mutations in Egyptian patients with acute myeloid leukemia with normal karyotype.Semantic proximity Read ↗

Impact of Wilms' tumor 1 gene (WT1) mutation on outcome of allogeneic hematopoietic-cell transplantation for acute myeloid leukemia: a retrospective multicenter cohort study from the ALWP/EBMT registry.Semantic proximity Read ↗

Friend or foe? The case of Wilms' Tumor 1 (WT1) mutations in acute myeloid leukemia.Semantic proximity Read ↗

Wilms Tumor 1 Mutations are Independent Poor Prognostic Factors in Pediatric Acute Myeloid LeukemiaSemantic proximity Read ↗

Mutational spectrum of acute myeloid leukemia patients with double CEBPA mutations based on next-generation sequencing and its prognostic significanceSemantic proximity Read ↗

Concomitant WT1 mutations predict poor prognosis in acute myeloid leukemia patients with double mutant CEBPASemantic proximity Read ↗

Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study.Semantic proximity Read ↗

WT1 mutation in pediatric patients with acute myeloid leukemia: a report from the Japanese Childhood AML Cooperative Study Group.Semantic proximity Read ↗

The clinical relevance of Wilms Tumour 1 (WT1) gene mutations in acute leukaemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.