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Article

Loss of transcription factor AP-2gamma/TFAP2C impairs branching morphogenesis of the murine mammary gland.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2010

Jäger Richard, Schäfer Sabine, Hau-Liersch Mathilde, Schorle Hubert

Abstract excerpt

Extensive development of the mammary gland occurs during puberty, when rising levels of ovarian hormones induce the formation of highly proliferative terminal end buds (TEBs) at the tips of mammary ducts. TEBs consist of an outer layer of cap cells and of inner body cells. TEBs invade the adipose stroma and bifurcate while extending the ducts to generate an arborized ductal network. We show that in murine mammary...

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Source

Identifiers

PMID: 20131354
DOI: 10.1002/dvdy.22239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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