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Article

Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland

1 Oct 2008

Abstract excerpt

BACKGROUND: The transcription factor DEAF-1 has been identified as a high affinity binding partner of the LIM-only protein LMO4 that plays important roles in mammary gland development and breast cancer. Here we investigated the influence of DEAF-1 on human and mouse mammary epithelial cells both in vitro and in vivo and identified a potential target gene. RESULTS: Overexpression of DEAF-1 in human breast...

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PMID: 18826651
DOI: 10.1186/1471-213x-8-94

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