Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability.

Cell research - 1 Dec 2013

Min Jin-Na, Tian Yanyan, Xiao Yang, Wu Ling, Li Lei, Chang Sandy

Abstract excerpt

The INO80 (inositol requiring mutant 80) chromatin remodeling complex plays important roles in transcriptional regulation and DNA replication and repair, and consists of several functional protein subunits, including the critical Ino80 ATPase catalytic subunit. While the function of INO80 has been studied in yeast and mammalian cell lines, we do not know how mIno80 contributes to the maintenance of genome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Senescence
Share to Chromatin Assembly and Disassembly

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Breaks, Double-Stranded

Share to DNA Helicases

Share to Genomic Instability

Share to Hydroxyurea

Share to Nucleic Acid Synthesis Inhibitors

Share to Telomere

Source

Open in PubMed Open full text

Identifiers

PMID: 23979016
DOI: 10.1038/cr.2013.113
PMCID: PMC3847565

Genes

INO80
ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability.PMID 23979016Read ↗

Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis.Semantic proximity Read ↗

Proficient repair in chromatin remodeling defective ino80 mutants of Saccharomyces cerevisiae highlights replication defects as the main contributor to DNA damage sensitivity.Semantic proximity Read ↗

The Ino80 chromatin-remodeling enzyme regulates replisome function and stability.Semantic proximity Read ↗

Involvement of mammalian Mus81 in genome integrity and tumor suppression.Semantic proximity Read ↗

The INO80 Chromatin Remodeler Sustains Metabolic Stability by Promoting TOR Signaling and Regulating Histone AcetylationSemantic proximity Read ↗

EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele.Semantic proximity Read ↗

INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.Semantic proximity Read ↗

The INO80 protein controls homologous recombination in Arabidopsis thaliana.Semantic proximity Read ↗

MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis.Semantic proximity Read ↗

The Myc-Like Mlx Network Impacts Aging and MetabolismSemantic proximity Read ↗

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together.Semantic proximity Read ↗

Function of the INO80 chromatin remodeling complex in DNA replication.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.