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Article

INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.

Cell - 17 Dec 2004

Morrison Ashby J, Highland Jessica, Krogan Nevan J, Arbel-Eden Ayelet, Greenblatt Jack F, Haber James E, Shen Xuetong

Abstract excerpt

While the role of ATP-dependent chromatin remodeling in transcription is well established, a link between chromatin remodeling and DNA repair has remained elusive. We have found that the evolutionarily conserved INO80 chromatin remodeling complex directly participates in the repair of a double-strand break (DSB) in yeast. The INO80 complex is recruited to a HO endonuclease-induced DSB through a specific...

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Share to Adenosine Triphosphate
Share to Chromatin Assembly and Disassembly

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Rad52 DNA Repair and Recombination Protein

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Source

Identifiers

PMID: 15607974
DOI: 10.1016/j.cell.2004.11.037

Genes

INO80
RAD52

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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