Article
GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics.
Human molecular genetics - 1 Jan 2014
Ledda Mirko, Kutalik Zoltán, Souza Destito Maria C, Souza Milena M, Cirillo Cintia A, Zamboni Amabilene, Martin Nathalie, Morya Edgard, Sameshima Koichi, Beckmann Jacques S, le Coutre Johannes, Bergmann Sven, Genick Ulrich K
Abstract excerpt
Human perception of bitterness displays pronounced interindividual variation. This phenotypic variation is mirrored by equally pronounced genetic variation in the family of bitter taste receptor genes. To better understand the effects of common genetic variations on human bitter taste perception, we conducted a genome-wide association study on a discovery panel of 504 subjects and a validation panel of 104...
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