Article
Allelic variation in TAS2R bitter receptor genes associates with variation in sensations from and ingestive behaviors toward common bitter beverages in adults.
Chemical senses - 1 Mar 2011
Hayes John E, Wallace Margaret R, Knopik Valerie S, Herbstman Deborah M, Bartoshuk Linda M, Duffy Valerie B
Abstract excerpt
The 25 human bitter receptors and their respective genes (TAS2Rs) contain unusually high levels of allelic variation, which may influence response to bitter compounds in the food supply. Phenotypes based on the perceived bitterness of single bitter compounds were first linked to food preference over 50 years ago. The most studied phenotype is propylthiouracil bitterness, which is mediated primarily by the TAS2R38...
Topics
- Adult
- Alcoholic Beverages
- Alleles
- Beverages
- Citrus paradisi
- Female
- Food Preferences
- Genetic Variation
- Humans
- Male
- Middle Aged