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Article

The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.

Human molecular genetics - 1 Nov 2010

Reed Danielle R, Zhu Gu, Breslin Paul A S, Duke Fujiko F, Henders Anjali K, Campbell Megan J, Montgomery Grant W, Medland Sarah E, Martin Nicholas G, Wright Margaret J

Abstract excerpt

The perceived taste intensities of quinine HCl, caffeine, sucrose octaacetate (SOA) and propylthiouracil (PROP) solutions were examined in 1457 twins and their siblings. Previous heritability modeling of these bitter stimuli indicated a common genetic factor for quinine, caffeine and SOA (22-28%), as well as separate specific genetic factors for PROP (72%) and quinine (15%). To identify the genes involved, we...

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Identifiers

PMID: 20675712
DOI: 10.1093/hmg/ddq324
PMCID: PMC2951861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.PMID 20675712Read ↗

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