Article
The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.
Human molecular genetics - 1 Nov 2010
Reed Danielle R, Zhu Gu, Breslin Paul A S, Duke Fujiko F, Henders Anjali K, Campbell Megan J, Montgomery Grant W, Medland Sarah E, Martin Nicholas G, Wright Margaret J
Abstract excerpt
The perceived taste intensities of quinine HCl, caffeine, sucrose octaacetate (SOA) and propylthiouracil (PROP) solutions were examined in 1457 twins and their siblings. Previous heritability modeling of these bitter stimuli indicated a common genetic factor for quinine, caffeine and SOA (22-28%)...
Topics
- Chromosomes, Human, Pair 12
- Genetic Variation
- Humans
- Polymorphism, Single Nucleotide
- Quinine
- Taste Buds