The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception.

doi:10.1016/j.cub.2005.01.047

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Article

The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception.

Current biology : CB - 22 Feb 2005

Bufe Bernd, Breslin Paul A S, Kuhn Christina, Reed Danielle R, Tharp Christopher D, Slack Jay P, Kim Un-Kyung, Drayna Dennis, Meyerhof Wolfgang

Abstract excerpt

Individual differences in perception are ubiquitous within the chemical senses: taste, smell, and chemical somesthesis . A hypothesis of this fact states that polymorphisms in human sensory receptor genes could alter perception by coding for functionally distinct receptor types . We have previous...

Topics

Animals
Blotting, Western
Cells, Cultured
DNA Mutational Analysis
DNA Primers
DNA, Complementary
Genetic Variation
Haplotypes
Humans
Immunohistochemistry
In Situ Hybridization
Least-Squares Analysis
Phenylthiourea
Propylthiouracil

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Receptors, Cell Surface

Receptors, G-Protein-Coupled

Reverse Transcriptase Polymerase Chain Reaction

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Identifiers

PMID: 15723792
DOI: 10.1016/j.cub.2005.01.047
PMCID: PMC1400547

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15723792-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.