Association between TLR3 rs3775291 and resistance to HIV among highly exposed Caucasian intravenous drug users.

doi:10.1016/j.meegid.2013.08.008

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Article

Association between TLR3 rs3775291 and resistance to HIV among highly exposed Caucasian intravenous drug users.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2013

Huik Kristi, Avi Radko, Pauskar Merit, Kallas Eveli, Jõgeda Ene-Ly, Karki Tõnis, Marsh Kristina, Des Jarlais Don, Uusküla Anneli, Lutsar Irja

Abstract excerpt

BACKGROUND: TLR3 recognizes dsRNA and triggers immune responses against RNA and DNA viruses. A polymorphism in TLR3, rs3775291 (Leu412Phe), has been associated with the increased susceptibility to enteroviral myocarditis, protection against tick-borne encephalitis virus and HIV-1 infection. We investigated Caucasian intravenous drug users (IDUs) and blood donors in order to evaluate the associations between TLR3...

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Identifiers

PMID: 23962581
DOI: 10.1016/j.meegid.2013.08.008
PMCID: PMC4001117

Genes

TLR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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