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Article

TLR3 polymorphisms are associated with virologic response to hepatitis C virus (HCV) treatment in HIV/HCV coinfected patients.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2015

Jiménez-Sousa María Angeles, Rallón Norma, Berenguer Juan, Pineda-Tenor Daniel, López Juan Carlos, Soriano Vicente, Guzmán-Fulgencio María, Cosín Jaime, Retana Diana, García-Álvarez Mónica, Miralles Pilar, Benito Jose Miguel, Resino Salvador

Abstract excerpt

BACKGROUND: Toll-like receptor-3 (TLR3) is a cellular receptor that may recognize double-stranded RNA (dsRNA) from viruses, resulting in production of proinflammatory cytokines and interferons, which are important for the adaptive immune response. OBJECTIVES: To analyze the association between Toll-like receptor-3 (TLR3) polymorphisms (rs3775291 and rs13126816) and virologic response to pegylated interferon-alpha...

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Source

Identifiers

PMID: 25766991
DOI: 10.1016/j.jcv.2015.02.004

Genes

TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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