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Article

Association of toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms with increased infection risk in patients with advanced HIV-1 infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Jul 2010

Papadopoulos Antonios I, Ferwerda Bart, Antoniadou Anastasia, Sakka Vissaria, Galani Lambrini, Kavatha Dimitra, Panagopoulos Periklis, Poulakou Garyphalia, Kanellakopoulou Kyriaki, van der Meer Jos W M, Giamarellos-Bourboulis Evangelos J, Netea Mihai G

Abstract excerpt

BACKGROUND. The Toll-like receptor 4 (TLR4) is an essential component of the innate immune response to various microorganisms. We investigated the association between TLR4 polymorphism and the risk of acquiring severe infections, in patients with human immunodeficiency virus (HIV)-1 infection. ME...

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Source

Identifiers

PMID: 20521908
DOI: 10.1086/653607

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20521908-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association of toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms with increased infection risk in patients with advanced HIV-1 infection.PMID 20521908Read ↗

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