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Article

Endosomal toll-like receptor gene polymorphisms and susceptibility to HIV and HCV co-infection - Differential influence in individuals with distinct ethnic background.

Human immunology - 1 Feb 2017

Valverde-Villegas Jacqueline M, Dos Santos Bruno Paiva, de Medeiros Rúbia Marília, Mattevi Vanessa Suñé, Lazzaretti Rosmeri Kuhmmer, Sprinz Eduardo, Kuhmmer Regina, Chies José Artur Bogo

Abstract excerpt

The genetic background of human populations can influence the susceptibility and outcome of infection diseases. Toll-like receptors (TLRs) have been previously associated with susceptibility to human immunodeficiency virus (HIV) infection, disease progression and hepatitis C, virus (HCV) co-infection in different populations, although mostly in Europeans. In this study, we investigated the genetic role of...

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Identifiers

PMID: 28062211
DOI: 10.1016/j.humimm.2017.01.001

Genes

TLR9
TLR7
TLR8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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