Article
Additive genetic variation in schizophrenia risk is shared by populations of African and European descent.
American journal of human genetics - 5 Sept 2013
de Candia Teresa R, Lee S Hong, Yang Jian, Browning Brian L, Gejman Pablo V, Levinson Douglas F, Mowry Bryan J, Hewitt John K, Goddard Michael E, O'Donovan Michael C, Purcell Shaun M, Posthuma Danielle, Visscher Peter M, Wray Naomi R, Keller Matthew C
Abstract excerpt
To investigate the extent to which the proportion of schizophrenia's additive genetic variation tagged by SNPs is shared by populations of European and African descent, we analyzed the largest combined African descent (AD [n = 2,142]) and European descent (ED [n = 4,990]) schizophrenia case-control genome-wide association study (GWAS) data set available, the Molecular Genetics of Schizophrenia (MGS) data set. We...
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