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Article

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.

Nature genetics - 19 Feb 2012

Lee S Hong, DeCandia Teresa R, Ripke Stephan, Yang Jian, Sullivan Patrick F, Goddard Michael E, Keller Matthew C, Visscher Peter M, Wray Naomi R

Abstract excerpt

Schizophrenia is a complex disorder caused by both genetic and environmental factors. Using 9,087 affected individuals, 12,171 controls and 915,354 imputed SNPs from the Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (PGC-SCZ), we estimate that 23% (s.e. = 1%) of variat...

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PMID: 22344220
DOI: 10.1038/ng.1108
PMCID: PMC3327879

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PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22344220-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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