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Article

Equivalent T cell epitope promiscuity in ecologically diverse human pathogens.

PloS one - 1 Jan 2013

Wiens Kirsten E, Swaminathan Harish, Copin Richard, Lun Desmond S, Ernst Joel D

Abstract excerpt

BACKGROUND: The HLA (human leukocyte antigen) molecules that present pathogen-derived epitopes to T cells are highly diverse. Correspondingly, many pathogens such as HIV evolve epitope variants in order to evade immune recognition. In contrast, another persistent human pathogen, Mycobacterium tuberculosis, has highly conserved epitope sequences. This raises the question whether there is also a difference in the...

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Share to Antigens, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23951341
DOI: 10.1371/journal.pone.0073124
PMCID: PMC3739752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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