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Article

Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B.

PLoS pathogens - 21 Sept 2007

Lewinsohn Deborah A, Winata Ervina, Swarbrick Gwendolyn M, Tanner Katie E, Cook Matthew S, Null Megan D, Cansler Meghan E, Sette Alessandro, Sidney John, Lewinsohn David M

Abstract excerpt

CD8(+) T cells are essential for host defense to intracellular bacterial pathogens such as Mycobacterium tuberculosis (Mtb), Salmonella species, and Listeria monocytogenes, yet the repertoire and dominance pattern of human CD8 antigens for these pathogens remains poorly characterized. Tuberculosis (TB), the disease caused by Mtb infection, remains one of the leading causes of infectious morbidity and mortality...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17892322
DOI: 10.1371/journal.ppat.0030127
PMCID: PMC2323292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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