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Article

HLA class I allele promiscuity revisited.

Immunogenetics - 1 Nov 2011

Rao Xiangyu, Hoof Ilka, Costa Ana Isabel C A Fontaine, van Baarle Debbie, Keşmir Can

Abstract excerpt

The peptide repertoire presented on human leukocyte antigen (HLA) class I molecules is largely determined by the structure of the peptide binding groove. It is expected that the molecules having similar grooves (i.e., belonging to the same supertype) might present similar/overlapping peptides. However, the extent of promiscuity among HLA class I ligands remains controversial: while in many studies T cell...

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Share to Alleles
Share to Antigen Presentation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21695550
DOI: 10.1007/s00251-011-0552-6
PMCID: PMC3190086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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