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Identification of a Promiscuous T-Cell Epitope inMycobacterium tuberculosisMce Proteins

1 Jan 2002

Abstract excerpt

The characterization of Mycobacterium tuberculosis antigens inducing CD4(+) T-cell responses could critically contribute to the development of subunit vaccines for M. tuberculosis. Here we performed computational analysis by using T-cell epitope prediction software (known as TEPITOPE) to predict promiscuous HLA-DR ligands in the products of the mce genes of M. tuberculosis. The analysis of the proliferative...

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PMID: 11748166
DOI: 10.1128/iai.70.1.79-85.2002

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