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Article

Hepatitis B virus genetic diversity.

Journal of medical virology - 1 Jan 2006

Echevarría José M, Avellón Ana

Abstract excerpt

Hepatitis B virus (HBV) is a human DNA virus, which replicates through an RNA intermediate because of the reverse-transcriptase (RT) activity of its DNA polymerase. As a result, the mutation rate for HBV is higher than the rate observed for most DNA viruses. HBVs are classified into genotypes based on genomic sequencing, and antigenic subtypes based on the antigenic properties of its major surface glycoprotein,...

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Identifiers

PMID: 16622876
DOI: 10.1002/jmv.20605

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