Article
Molecular epidemiology of hepatitis B virus.
The Korean journal of internal medicine - 1 Sept 2011
Kao Jia-Horng
Abstract excerpt
Although safe and effective vaccines for hepatitis B virus (HBV) have been available for nearly three decades, this virus kills at least 600,000 people annually worldwide and remains the leading global cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Because the HBV reverse transcriptase lacks a proofreading function, many HBV genotypes, subgenotypes, mutants, and recombinants exist. At least...
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