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Article

Assumptions and properties of limiting pathway models for analysis of epistasis in complex traits.

PloS one - 1 Jan 2013

Stringer Sven, Derks Eske M, Kahn René S, Hill William G, Wray Naomi R

Abstract excerpt

For most complex traits, results from genome-wide association studies show that the proportion of the phenotypic variance attributable to the additive effects of individual SNPs, that is, the heritability explained by the SNPs, is substantially less than the estimate of heritability obtained by s...

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Identifiers

PMID: 23935903
DOI: 10.1371/journal.pone.0068913
PMCID: PMC3728313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23935903-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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