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Article

A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014

Cao Lei, Lin Jia, He Bing, Wang Hongge, Rao Juan, Liu Yingwen, Zhang Xuemei

Abstract excerpt

Cytochrome P450 2E1 (CYP2E1), an ethanol-inducible enzyme, has been shown to metabolically activate various carcinogens, which is critical for the development of cancers. It has been demonstrated that CYP2E1 polymorphisms alter the transcriptional activity. However, studies on the association between CYP2E1 -1239G>C polymorphism and non-small cell lung cancer have reported conflicting results. Thus, the gain of...

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Identifiers

PMID: 23934444
DOI: 10.1007/s13277-013-1063-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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