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Article

Variants in CYP2J2 and CYP2C9 Contribute to Susceptibility of Lung Cancer.

Current cancer drug targets - 1 Jan 2025

Zhang Chan, Li Qi, Cheng Yujing, Yang Xin, Chen Wanlu, He Kunhua, Chen Mingwei

Abstract excerpt

BACKGROUND: Cytochrome P450 (CYP) enzymes are involved in the metabolism of xenobiotic and carcinogen. In the study, we evaluated the association of CYP2J2 and CYP2C9 variants with lung cancer. METHODS: Five polymorphisms in CYP2J2 and four polymorphisms in CYP2C9 were genotyped in 507 lung cancer patients and 505 controls with Agena MassARRAY platform. The linkage of variants with lung cancer risk was evaluated...

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Source

Identifiers

PMID: 36380410
DOI: 10.2174/1568009623666221114115012

Genes

CYP2C9
CYP2J2
TG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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