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Article

Genetic polymorphisms in cytochrome P450 genes are associated with an increased risk of squamous cell carcinoma of the larynx and hypopharynx in a Chinese population.

Cancer genetics and cytogenetics - 1 Jan 2010

Tai Jun, Yang Ming, Ni Xin, Yu Dianke, Fang Jugao, Tan Wen, Huang Zhigang, Wu Chen, Chen Xiaohong, Wang Guanghai, Zhou Weiguo, Chen Xuejun, Zhang Wei, Ma Lijing, Lin Dongxin, Han Demin

Abstract excerpt

The purpose of this study was to examine whether functional polymorphisms in the cytochrome P450 (CYP) enzyme genes affect the risk of developing larynx and hypopharynx squamous cell carcinoma (SCC). We investigated CYP1A1, CYP1B1, CYP2E1, and CYP3A4 polymorphisms in 278 patients with laryngeal and hypopharyngeal SCC and 278 control subjects by polymerase chain reaction-restriction fragment length polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19963139
DOI: 10.1016/j.cancergencyto.2009.08.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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