Article
Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer.
BMC cancer - 30 Jun 2007
Fan Chunhong, Jin Mingjuan, Chen Kun, Zhang Yongjing, Zhang Shuangshuang, Liu Bing
Abstract excerpt
BACKGROUND: Gene-gene and gene-environment interactions involved in the metabolism of carcinogens may increase the risk of cancer. Our objective was to measure the interactions between common polymorphisms of P450 (CYP1A2, CYP1B1, CYP2E1), GSTM1 and T1, SULT1A1 and cigarette smoking in colorectal cancer (CRC). METHODS: A case-only design was conducted in a Chinese population including 207 patients with sporadic...
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