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Article

Genotype and allele frequencies of MDR1 gene C1236T polymorphism in a Turkish population.

Genetics and molecular research : GMR - 28 Oct 2008

Gümüş-Akay G, Rüstemoğlu A, Karadağ A, Sunguroğlu A

Abstract excerpt

Human P-glycoprotein (P-gp) is encoded by the MDR1 gene, which is located on chromosomal region 7q21 and consists of 28 exons. To date, over 50 single nucleotide polymorphisms (SNPs) have been reported for the MDR1 gene. The effect of these polymorphisms on P-gp function or their clinical impact is in most cases unknown, but some of the SNPs are known to be of functional relevance and can also alter the...

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PMID: 19048498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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