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Article

Blockade of the human ether-a-go-go-related gene potassium channel by ketamine.

The Journal of pharmacy and pharmacology - 1 Sept 2013

Zhang Peihua, Xing Junlian, Luo Antao, Feng Juan, Liu Zhipei, Gao Chenghao, Ma Jihua

Abstract excerpt

OBJECTIVES: The inhibition of the cardiac rapid delayed rectifier potassium current (IKr ) and its cloned equivalent human ether-a-go-go-related gene (hERG) channel illustrate QT interval prolonging effects of a wide range of clinically used drugs. In this study, the direct interaction of the int...

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Source

Identifiers

PMID: 23927470
DOI: 10.1111/jphp.12095

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23927470-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Blockade of the human ether-a-go-go-related gene potassium channel by ketamine.PMID 23927470Read ↗

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