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Article

Loss of NAC1 expression is associated with defective bony patterning in the murine vertebral axis.

PloS one - 1 Jan 2013

Yap Kai Lee, Sysa-Shah Polina, Bolon Brad, Wu Ren-Chin, Gao Min, Herlinger Alice L, Wang Fengying, Faiola Francesco, Huso David, Gabrielson Kathleen, Wang Tian-Li, Wang Jianlong, Shih Ie-Ming

Abstract excerpt

NAC1 encoded by NACC1 is a member of the BTB/POZ family of proteins and participates in several pathobiological processes. However, its function during tissue development has not been elucidated. In this study, we compared homozygous null mutant Nacc1(-/-) and wild type Nacc1(+/+) mice to determine the consequences of diminished NAC1 expression. The most remarkable change in Nacc1(-/-) mice was a vertebral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23922682
DOI: 10.1371/journal.pone.0069099
PMCID: PMC3724875

Genes

NACC1

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