Contribution of ADD3 and the HLA Genes to Biliary Atresia Risk in Chinese.

doi:10.3390/ijms241914719

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Article

Contribution of ADD3 and the HLA Genes to Biliary Atresia Risk in Chinese.

International journal of molecular sciences - 29 Sept 2023

Cui Meng-Meng, Gong Yi-Ming, Pan Wei-Hua, Pei Hao-Yue, Bai Mei-Rong, Song Huan-Lei, Han Xin-Ru, Wu Wen-Jie, Yu Wen-Wen, Gu Bei-Lin, Cai Wei, Zhou Ying, Chu Xun

Abstract excerpt

Nonsyndromic biliary atresia (BA) is a rare polygenic disease, with autoimmunity, virus infection and inflammation thought to play roles in its pathogenesis. We conducted a genome-wide association study in 336 nonsyndromic BA infants and 8900 controls. Our results validated the association of rs17095355 in ADD3 with BA risk (odds ratio (OR) = 1.70, 95% confidence interval (95% CI) = 1.49-1.99; p = 4.07 × 10-11)....

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Identifiers

PMID: 37834180
DOI: 10.3390/ijms241914719
PMCID: PMC10572496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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