Article
Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3.
American journal of medical genetics. Part A - 1 Apr 2010
Leyva-Vega Melissa, Gerfen Jennifer, Thiel Brian D, Jurkiewicz Dorota, Rand Elizabeth B, Pawlowska Joanna, Kaminska Diana, Russo Pierre, Gai Xiaowu, Krantz Ian D, Kamath Binita M, Hakonarson Hakon, Haber Barbara A, Spinner Nancy B
Abstract excerpt
Biliary atresia (BA) is a progressive, idiopathic obliteration of the extrahepatic biliary system occurring exclusively in the neonatal period. It is the most common disease leading to liver transplantation in children. The etiology of BA is unknown, although infectious, immune and genetic causes have been suggested. Although the recurrence of BA in families is not common, there are more than 30 multiplex...
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