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Article

Immune-mediated disease genetics: the shared basis of pathogenesis.

Trends in immunology - 1 Jan 2013

Cotsapas Chris, Hafler David A

Abstract excerpt

Recent genetic studies in multiple autoimmune and inflammatory diseases have identified hundreds of genomic loci harboring risk variants. These variants are shared between diseases at unexpectedly high rates, providing a molecular basis for the shared pathogenesis of immune-mediated disease. If properly used, these results could allow us to identify specific pathways underlying disease; explain disease...

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PMID: 23031829
DOI: 10.1016/j.it.2012.09.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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