Article
Identifying susceptibility genes for immunological disorders: patterns, power, and proof.
Immunological reviews - 1 Apr 2006
Plenge Robert, Rioux John D
Abstract excerpt
There is a genetic basis to the most common immune-mediated diseases. Identifying disease susceptibility genes, however, has been a challenge. Only a few genes have been consistently replicated across multiple studies. These convincing examples provide insight into a genetic approach to common immune diseases as well as insight into disease pathogenesis. Here, we discuss several important concepts of a genetic...
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