Article
A single-nucleotide polymorphism of the TNFAIP3 gene is associated with systemic lupus erythematosus in Chinese Han population.
Molecular biology reports - 1 Jan 2010
Cai Li-Qiong, Wang Zai-Xing, Lu Wen-Sheng, Han Jian-Wen, Sun Liang-Dan, Du Wen-Hui, Zhang Shu-Mei, Zuo Xian-Bo, Zhang Xue-Jun, Yang Sen
Abstract excerpt
Systemic lupus erythematosus (SLE) is a complex systemic disease influenced by genetic and environmental factors. The exact pathogenesis of SLE is still unknown. Recently, several genome-wide association studies (GWA) in European population have found many novel susceptibility genes for SLE including TNFAIP3. In order to examine whether TNFAIP3 is associated with SLE in Chinese Han population, we genotyped one of...
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