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Article

Perigestational dietary folic acid deficiency protects against medulloblastoma formation in a mouse model of nevoid basal cell carcinoma syndrome.

Nutrition and cancer - 1 Jan 2013

Been Raha A, Ross Julie A, Nagel Christian W, Hooten Anthony J, Langer Erica K, DeCoursin Krista J, Marek Courtney A, Janik Callie L, Linden Michael A, Reed Robyn C, Schutten Melissa M, Largaespada David A, Johnson Kimberly J

Abstract excerpt

Hereditary nevoid basal cell carcinoma syndrome (NBCCS) is caused by PTCH1 gene mutations that result in diverse neoplasms including medulloblastoma (MB). Epidemiological studies report reduced pediatric brain tumor risks associated with maternal intake of prenatal vitamins containing folic acid...

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Source

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Identifiers

PMID: 23909730
DOI: 10.1080/01635581.2013.804940
PMCID: PMC3771499

Genes

PTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23909730-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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