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Article

Effect of folic acid on animal models, cell cultures, and human oral clefts: a literature review

2020-11-26

Abstract excerpt

Abstract Background Folate is a naturally occurring, water-soluble B vitamin. The synthetic form of this compound is folic acid (FA), the deficiency of which is linked to neural tube disorders (NTD), which can be prevented by consuming it before, or during the early months of, pregnancy. However, the effect of FA on oral cleft formation remains controversial. The aim of the present study was to review the evidence...

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Literature Corpus work
720cb336-c104-5049-8b54-ba29483a0eab
DOI
10.1186/s43042-020-00108-x
Open publication

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Effect of folic acid on animal models, cell cultures, and human oral clefts: a literature reviewDOI 10.1186/s43042-020-00108-x
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