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Article

An osteopontin promoter polymorphism is associated with aggressiveness in breast cancer.

Oncology reports - 1 Oct 2013

Ramchandani Divya, Weber Georg F

Abstract excerpt

Metastasis-related genes are deregulated in cancer by aberrant expression or splicing. Here, we analyzed polymorphic sites in the osteopontin promoter as potential contributors to aberrant expression in breast cancers. This study comprised 241 breast cancer specimens, for which DNA from normal surrounding tissue was available for 111, and 65 healthy breast samples. The polymorphic site in position -443 of the...

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Identifiers

PMID: 23900428
DOI: 10.3892/or.2013.2632

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