Article
Genetic polymorphisms in the osteopontin promoter increases the risk of distance metastasis and death in Chinese patients with gastric cancer.
BMC cancer - 16 Oct 2012
Zhao Fujun, Chen Xiaoyi, Meng Tingting, Hao Bo, Zhang Zhihong, Zhang Guoxin
Abstract excerpt
BACKGROUND: In vitro and in vivo studies have suggested that osteopontin (OPN) is associated with many types of cancers. However, no studies have reported the incidence of OPN polymorphisms and the risk of gastric cancer. The aim of this study was to investigate the association between OPN polymorphisms and gastric cancer in a Chinese patient population. METHODS: Three genetic variants in the OPN promoter were...
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