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Article

The implication of osteopontin (OPN) expression and genetic polymorphisms of OPN promoter in oral carcinogenesis.

Oral oncology - 1 Apr 2010

Chiu Yu-Wei, Tu Hsi-Feng, Wang I-Kai, Wu Cheng-Hsien, Chang Kuo-Wei, Liu Tsung-Yun, Kao Shou-Yen

Abstract excerpt

Osteopontin (OPN) is an extracellular matrix protein in hard tissues. The polymorphism in promoter region of OPN gene correlates to different gene expression and might implicate potential roles in tumor progression and metastasis. Immunohistochemistry (IHC) was utilized to detect the OPN expression in 58 oral squamous cell carcinoma (OSCC) tissues and adjacent normal oral mucosa. The differential OPN expression...

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Source

Identifiers

PMID: 20219412
DOI: 10.1016/j.oraloncology.2010.01.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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