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Article

Osteopontin promoter polymorphisms at locus -443 significantly affect the metastasis and prognosis of human hepatocellular carcinoma.

Hepatology (Baltimore, Md.) - 1 Mar 2013

Dong Qiong-Zhu, Zhang Xiao-Fei, Zhao Yue, Jia Hu-Liang, Zhou Hai-Jun, Dai Chun, Sun Hai-Jing, Qin Yi, Zhang Wei-De, Ren Ning, Ye Qing-Hai, Qin Lun-Xiu

Abstract excerpt

UNLABELLED: Osteopontin (OPN) plays a crucial role in hepatocellular carcinoma (HCC) metastasis. However, little is known about the impact of OPN polymorphisms on cancer progression. In this study, we first identified the single nucleotide polymorphisms (SNPs) in the OPN promoter region by direct sequencing in 30 HCCs, and then evaluated the prognostic values of the selected ones in two large cohorts of 826 HCC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23079960
DOI: 10.1002/hep.26103

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TTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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