Article

Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules

2020-09-28

Abstract excerpt

Protein-protein interactions (PPIs) are involved in many of life’s essential biological functions yet are also an underlying cause of several human diseases, including amyloidosis. The modulation of PPIs presents opportunities to gain mechanistic insights into amyloid assembly, particularly through the use of methods which can trap specific intermediates for detailed study. Such information can also provide a...

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Literature Corpus work: 0c95766c-597c-52fa-84a5-ec7652b438d1
DOI: 10.26434/chemrxiv.13008212.v1

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