Article
Increased susceptibility to mild neonatal stress in MTHFR deficient mice.
Behavioural brain research - 15 Sept 2013
Kezurer N, Galron D, Golan H M
Abstract excerpt
Early life stress is shown to have a life-span outcome on human and animal behavior, increasing the risk for psychopathology. The gene methylenetetrahydrofolate reductase (MTHFR), which encodes for a key enzyme in one carbon metabolism, shows a high prevalence of polymorphism in patients with developmental disorders. Here we examined the hypothesis that MTHFR deficiency results in an increased susceptibility of...
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