Article
Maternal stress in Shank3ex4-9 mice increases pup-directed care and alters brain white matter in male offspring.
PloS one - 1 Jan 2019
Wong Bibiana K Y, Murry Jaclyn B, Ramakrishnan Rajesh, He Fang, Balasa Alfred, Stinnett Gary R, Pedersen Steen E, Pautler Robia G, Van den Veyver Ignatia B
Abstract excerpt
Gene-environment interactions contribute to the risk for Autism Spectrum Disorder (ASD). Among environmental factors, prenatal exposure to stress may increase the risk for ASD. To examine if there is an interaction between exposure to maternal stress and reduced dosage or loss of Shank3, wild-type (WT), heterozygous (HET) and homozygous (HOM) female mice carrying a deletion of exons four through nine of Shank3...
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