Back to search

Article

The Impact of Mild Chronic Stress and Maternal Experience in the Fmr1 Mouse Model of Fragile X Syndrome

2023-05-31

Abstract excerpt

Fragile X Syndrome (FXS) is a pervasive developmental disorder and the most common monogenic cause of autism spectrum disorder (ASD). Female heterozygous (HET) carriers play a major role in the transmission of the pathology and present several FXS- and ASD-like behavioral alterations. Despite their clear genetic origins, FXS symptoms are known to be modulated by environmental factors, e.g., the exposure to chronic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
063eb4f6-6314-5f8c-b723-282f59be0228
DOI
10.20944/preprints202305.2223.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Impact of Mild Chronic Stress and Maternal Experience in the Fmr1 Mouse Model of Fragile X SyndromeDOI 10.20944/preprints202305.2223.v1
Autistic-like behavioral effects of prenatal stress in juvenile Fmr1 mice: the relevance of sex differences and gene-environment interactionsSemantic proximity
Deletion of Fmr1 results in sex-specific changes in behavior.Semantic proximity
Exploring Behavioral and Neural Dynamics of Social Interactions during the Juvenile Stage in a Mouse Model of Fragile X SyndromeSemantic proximity
A novel murine model to study the impact of maternal depression and antidepressant treatment on biobehavioral functions in the offspringSemantic proximity
Influence of Early Stress on Social Abilities and Serotonergic Functions across Generations in MiceSemantic proximity
Social behavior phenotypes in fragile X syndrome, autism, and the Fmr1 knockout mouse: theoretical comment on McNaughton et al. (2008).Semantic proximity
Impact of <i>Fkbp5</i> × Early Life Adversity × Sex in Humanized Mice on Multidimensional Stress Responses and Circadian RhythmicitySemantic proximity
Chronic prenatal corticosterone exposure alters postpartum maternal behavior and shapes sex-specific offspring outcomesSemantic proximity
Prenatal stress interacts with embryonic loss of <i>Fgfr2</i> to increase locomotor hyperactivity in miceSemantic proximity
Impact of Fkbp5 × early life adversity × sex in humanised mice on multidimensional stress responses and circadian rhythmicity.Semantic proximity
The Consequences of Early‐Life Adversity: Neurobiological, Behavioural and Epigenetic AdaptationsSemantic proximity
Behavioral analysis of male and female Fmr1 knockout mice on C57BL/6 background.Semantic proximity
Select a neighboring publication to make it the new centre.