Article
The associations between a polygenic score, reproductive and menstrual risk factors and breast cancer risk.
Breast cancer research and treatment - 1 Jul 2013
Warren Andersen Shaneda, Trentham-Dietz Amy, Gangnon Ronald E, Hampton John M, Figueroa Jonine D, Skinner Halcyon G, Engelman Corinne D, Klein Barbara E, Titus Linda J, Newcomb Polly A
Abstract excerpt
We evaluated whether 13 single nucleotide polymorphisms (SNPs) identified in genome-wide association studies interact with one another and with reproductive and menstrual risk factors in association with breast cancer risk. DNA samples and information on parity, breastfeeding, age at menarche, age at first birth, and age at menopause were collected through structured interviews from 1,484 breast cancer cases and...
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