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Article

Transmission of breast cancer polygenic risk based on single nucleotide polymorphisms.

Breast (Edinburgh, Scotland) - 1 Oct 2018

Cox David G, Heudel Pierre-Etienne, Henry Julie, Pivot Xavier

Abstract excerpt

AIM: The goal of the present study was to further refine how polygenic risk scores may be used in a large population and to quantify the transmission of risk score through generations. METHODS: Allele frequencies from the 1000 Genomes data for 159 single nucleotide polymorphisms associated with breast cancer risk were used. A breast cancer risk score was calculated among 100,000 people. Choosing two "parents" and...

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Identifiers

PMID: 29933179
DOI: 10.1016/j.breast.2018.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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