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Article

A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.

Breast cancer research and treatment - 1 Jan 2015

Vachon Celine M, Schaid Daniel J, Ingle James N, Wickerham D Lawrence, Kubo Michiaki, Mushiroda Taisei, Goetz Matthew P, Carlson Erin E, Paik Soonmyung, Wolmark Norman, Nakamura Yusuke, Wang Liewei, Weinshilboum Richard, Couch Fergus J

Abstract excerpt

Recent genetic studies have identified common variation in susceptibility loci that stratify lifetime risks of breast cancer and may inform prevention and screening strategies. However, whether these loci have similar implications for women treated with tamoxifen or raloxifene (SERMs) is unknown. We conducted a matched case-control study of 592 cases who developed breast cancer and 1,171 unaffected women from...

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Identifiers

PMID: 25575444
DOI: 10.1007/s10549-014-3175-4
PMCID: PMC4327931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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