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Article

TrAp: a tree approach for fingerprinting subclonal tumor composition.

Nucleic acids research - 1 Sept 2013

Strino Francesco, Parisi Fabio, Micsinai Mariann, Kluger Yuval

Abstract excerpt

Revealing the clonal composition of a single tumor is essential for identifying cell subpopulations with metastatic potential in primary tumors or with resistance to therapies in metastatic tumors. Sequencing technologies provide only an overview of the aggregate of numerous cells. Computational approaches to de-mix a collective signal composed of the aberrations of a mixed cell population of a tumor sample into...

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Identifiers

PMID: 23892400
DOI: 10.1093/nar/gkt641
PMCID: PMC3783191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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